This thesis will deal with various aspects of an extremely widespread disease in the population and one of the main causes of death in the world: the abdominal aortic aneurysm (AAA). The first part will be dedicated to the generalities of the aortic aneurysm. The second part is focused on the endovascular treatment of the aortic aneurysm (EVAR), which is the most commonly used method for the repair of AAAs and which represents a therapeutic advance compared to traditional open surgery (OSR). In the third part of the thesis the main theme is addressed: the follow-up after endovascular treatment. The post EVAR follow-up aims to evaluate not only the success of the operation, therefore the short-term results, but above all the long-term ones, identifying recurrent diseases and complications that can lead to patient morbidity and mortality. Several investigation tools are available for this purpose, but the examination of choice to date is still Computed Tomography Angiography (CTA), although several studies have been performed, and many are still in progress, in order to replace the CTA with less harmful methods such as ultrasound with Duplex Ultrasound (DUS), or Contrast Ehnanced Ultrasound (CEUS). Each of these methods will be analyzed, the guidelines currently available on the subject will be presented, and numerous articles and reviews, among the most recent and significant, concerning various aspects of post-EVAR follow-up will be considered.
In questa tesi si andranno a trattare diversi aspetti di una patologia estremamente diffusa nella popolazione e che rappresenta una delle cause principali di morte nel mondo: l’aneurisma dell’aorta addominale (AAA= Abdominal Aortic Aneurysm). La prima parte della tesi, verrà dedicata alle generalità dell’aneurisma aortico. La seconda parte della tesi è focalizzata sul trattamento endovascolare dell’aneurisma aortico (EVAR), che rappresenta la metodica più comunemente utilizzata per la riparazione degli AAA e che rappresenta un avanzamento terapeutico rispetto alla chirurgia tradizionale aperta (Open Surgical Repair=OSR). Nella terza parte della tesi si affronta il tema principale: il follow-up dopo trattamento endovascolare. Il follow-up post EVAR ha lo scopo di valutare non soltanto la buona riuscita dell’operazione, quindi i risultati a breve termine, ma soprattutto a lungo termine, individuando le malattie ricorrenti e le complicanze che possono portare alla morbilità e alla mortalità del paziente. Diversi strumenti di indagine sono disponibili a questo scopo, ma l’esame di scelta ad oggi è ancora la tomografia computerizzata con mezzo di contrasto (CTA= Computed Tomography Angiography), anche se diversi studi sono stati eseguiti, e numerosi sono ancora in corso, allo scopo di sostituire la CTA con metodiche meno dannose come ad esempio l’ecografia con eco color doppler (DUS= Duplex Ultrasound), o l’ecografia con mezzo di contrasto (CEUS= Contrast Ehnanced Ultrasound). Verranno analizzate ognuna di queste metodiche, verranno esposte le linee guida attualmente disponibili sul tema, e verranno presi in considerazione numerosi articoli e review, fra le più recenti e significative, riguardanti diversi aspetti del follow-up post EVAR.
VALUTAZIONE DEI PERCORSI DI FOLLOW-UP POST EVAR
PENASA, FRANCESCO
2020/2021
Abstract
This thesis will deal with various aspects of an extremely widespread disease in the population and one of the main causes of death in the world: the abdominal aortic aneurysm (AAA). The first part will be dedicated to the generalities of the aortic aneurysm. The second part is focused on the endovascular treatment of the aortic aneurysm (EVAR), which is the most commonly used method for the repair of AAAs and which represents a therapeutic advance compared to traditional open surgery (OSR). In the third part of the thesis the main theme is addressed: the follow-up after endovascular treatment. The post EVAR follow-up aims to evaluate not only the success of the operation, therefore the short-term results, but above all the long-term ones, identifying recurrent diseases and complications that can lead to patient morbidity and mortality. Several investigation tools are available for this purpose, but the examination of choice to date is still Computed Tomography Angiography (CTA), although several studies have been performed, and many are still in progress, in order to replace the CTA with less harmful methods such as ultrasound with Duplex Ultrasound (DUS), or Contrast Ehnanced Ultrasound (CEUS). Each of these methods will be analyzed, the guidelines currently available on the subject will be presented, and numerous articles and reviews, among the most recent and significant, concerning various aspects of post-EVAR follow-up will be considered.È consentito all'utente scaricare e condividere i documenti disponibili a testo pieno in UNITESI UNIPV nel rispetto della licenza Creative Commons del tipo CC BY NC ND.
Per maggiori informazioni e per verifiche sull'eventuale disponibilità del file scrivere a: unitesi@unipv.it.
https://hdl.handle.net/20.500.14239/13289