Hyperhidrosis is a condition of excessive sweating that affects the whole body, particularly the palmar, plantar, axillary and craniofacial regions. Many people around the world suffer from this disorder, but being a disorder that is neglected, misunderstood and put aside, the percentage of patients who report it is lower. The most accredited hypothesis of the origin of hyperhidrosis seems to be sympathetic hyperactivity and hyperexcitability of the eccrine sweat glands. Hyperhidrosis can be classified as primary, a condition in which there is excessive sweating in a specific area of the body and has no medical comorbidity and is not related to pharmacy intake as a side effect, and secondary, a manifestation of secondary excessive sweating. to something, it can be caused by a clinical condition (pregnancy, menopause, diabetes, Frey syndrome, hyperthyroidism, hypoglycemia, HIV, alcoholism) or by drugs (ntidepressants, triptans, antipyretics, cholinergics, hypoglycemic agents and sympathomimetic agents). It can be diagnostic with both quantitative (gravimetry, evaporimetry, Minor's test) and qualitative methods of analysis. This disorder can also be psychosomatic in nature, in fact, in addition to professionals such as cosmetic surgeons, dermatologists, pharmacists and neurologists, it is important to include the professional figure of the psychologist, in an attempt to find a cure / relief for this debilitating condition for the quality of life of who suffers from it. Therapeutic alternatives include pharmacological treatments (antiperspirants, topical agents, oral anticholinergics), cosmetics (intradermal injections of botulinum toxin, iontophoresis and microwave device), surgical (transthoracic sympathectomy endoscopy and local surgery). Treatment algorithms have been drawn up for the different types of hyperhidrosis that can be used by specialist doctors and patients to choose the best therapy. In this thesis, in addition to the treatments already available, the possible correlation between excessive sweating and the foods that can trigger a response to this, both positive and negative, has been analyzed.
L'iperidrosi è una condizione di eccessiva sudorazione che interessa tutto il corpo, in particolare le regioni palmare, plantare, ascellare e craniofacciale. Molte persone nel mondo soffrono di questo disturbo, ma essendo un disturbo che viene trascurato, non capito e messo da parte, la percentuale di pazienti che lo denunciano è inferiore. Ipotesi più accreditata dell’origine dell’iperidrosi sembra essere un’iperattività e ipereccitabilità simpatica delle ghiandole sudoripare eccrine. L’iperidrosi può essere classificata come primaria, condizione in cui vi è un’eccessiva sudorazione in una zona specifica corporea e non ha nessuna comorbilità medica e non è correlata all’assunzione di farmacia come effetto collaterale, e secondaria, manifestazione di eccessiva sudorazione secondaria a qualcosa, può essere causata da una condizione clinica (gravidanza, menopausa, diabete, sindrome di Frey, ipertiroidismo, ipoglicemia, HIV, alcolismo) o da farmaci (ntidepressivi, triptani, antipiretici, colinergici, agenti ipoglicemizzanti e agenti simpaticomimetici). Può essere diagnostica con metodi di analisi sia quantitativi (gravimetria, evaporimetria, test di Minor) che qualitativi. Questo disturbo può essere anche di natura psicosomatica, infatti oltre a professionisti quali chirurghi estetici, dermatologi, farmacisti e neurologi, è importante inserire la figura professionale dello psicologo, nel tentativo di trovare una cura/sollievo a questa condizione debilitante per la qualità della vita di chi ne soffre. Le alternative terapeutiche includono trattamenti farmacologici (antitraspiranti, agenti topici, anticolinergici orali), cosmetici (iniezioni intradermiche di tossina botulinica, ionoforesi e dispositivo a microonde), chirurgici (simpaticectomia transtoracica endoscopia e chirurgia locale). Sono stati stilati degli algoritmi di trattamento per le diverse tipologie di iperidrosi che possono essere utilizzati d medici specialisti e pazienti per andare a scegliere la terapia migliore. In questa tesi, oltre ai trattamenti già disponibili, si è analizzata la possibile correlazione tra la sudorazione eccessiva e gli alimenti che possono scatenare una risposta a questa, sia positiva che negativa.
L'iperidrosi
VERCELLI, MARTINA
2020/2021
Abstract
Hyperhidrosis is a condition of excessive sweating that affects the whole body, particularly the palmar, plantar, axillary and craniofacial regions. Many people around the world suffer from this disorder, but being a disorder that is neglected, misunderstood and put aside, the percentage of patients who report it is lower. The most accredited hypothesis of the origin of hyperhidrosis seems to be sympathetic hyperactivity and hyperexcitability of the eccrine sweat glands. Hyperhidrosis can be classified as primary, a condition in which there is excessive sweating in a specific area of the body and has no medical comorbidity and is not related to pharmacy intake as a side effect, and secondary, a manifestation of secondary excessive sweating. to something, it can be caused by a clinical condition (pregnancy, menopause, diabetes, Frey syndrome, hyperthyroidism, hypoglycemia, HIV, alcoholism) or by drugs (ntidepressants, triptans, antipyretics, cholinergics, hypoglycemic agents and sympathomimetic agents). It can be diagnostic with both quantitative (gravimetry, evaporimetry, Minor's test) and qualitative methods of analysis. This disorder can also be psychosomatic in nature, in fact, in addition to professionals such as cosmetic surgeons, dermatologists, pharmacists and neurologists, it is important to include the professional figure of the psychologist, in an attempt to find a cure / relief for this debilitating condition for the quality of life of who suffers from it. Therapeutic alternatives include pharmacological treatments (antiperspirants, topical agents, oral anticholinergics), cosmetics (intradermal injections of botulinum toxin, iontophoresis and microwave device), surgical (transthoracic sympathectomy endoscopy and local surgery). Treatment algorithms have been drawn up for the different types of hyperhidrosis that can be used by specialist doctors and patients to choose the best therapy. In this thesis, in addition to the treatments already available, the possible correlation between excessive sweating and the foods that can trigger a response to this, both positive and negative, has been analyzed.È consentito all'utente scaricare e condividere i documenti disponibili a testo pieno in UNITESI UNIPV nel rispetto della licenza Creative Commons del tipo CC BY NC ND.
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https://hdl.handle.net/20.500.14239/14332