Ricerca avanzata

This medical thesis investigates the pivotal role of Programmed Death-Ligand 1 (PDL-1) in the progression and recurrence of high-grade cervical intraepithelial neoplasia (CIN). Focusing on the intricate interplay between human papillomavirus (HPV) and its manifestation as CIN, the study delves into the molecular mechanisms underlying the correlation between the HPV-induced CIN and PDL-1, a key player in the programmed death pathway. The thesis synthesizes current knowledge, offering a comprehensive review to enhance our understanding of the complex interactions driving the development and persistence of high-grade CIN, with implications for potential therapeutic interventions and targeted approaches in cervical cancer management

This medical thesis investigates the pivotal role of Programmed Death-Ligand 1 (PDL-1) in the progression and recurrence of high-grade cervical intraepithelial neoplasia (CIN). Focusing on the intricate interplay between human papillomavirus (HPV) and its manifestation as CIN, the study delves into the molecular mechanisms underlying the correlation between the HPV-induced CIN and PDL-1, a key player in the programmed death pathway. The thesis synthesizes current knowledge, offering a comprehensive review to enhance our understanding of the complex interactions driving the development and persistence of high-grade CIN, with implications for potential therapeutic interventions and targeted approaches in cervical cancer management

The Significance of Programmed Death-Ligand 1 (PDL-1) in High-Grade Cervical Intraepithelial Neoplasia (CIN2+) Development and Recurrence: A Systematic Review of Literature about HPV-CIN2-PDL-1 Axis

ELDAR, ASAF
2023/2024

Abstract

This medical thesis investigates the pivotal role of Programmed Death-Ligand 1 (PDL-1) in the progression and recurrence of high-grade cervical intraepithelial neoplasia (CIN). Focusing on the intricate interplay between human papillomavirus (HPV) and its manifestation as CIN, the study delves into the molecular mechanisms underlying the correlation between the HPV-induced CIN and PDL-1, a key player in the programmed death pathway. The thesis synthesizes current knowledge, offering a comprehensive review to enhance our understanding of the complex interactions driving the development and persistence of high-grade CIN, with implications for potential therapeutic interventions and targeted approaches in cervical cancer management
DIPARTIMENTO DI MEDICINA MOLECOLARE
2023
The Significance of Programmed Death-Ligand 1 (PDL-1) in High-Grade Cervical Intraepithelial Neoplasia (CIN2+) Development and Recurrence: A Systematic Review of Literature about HPV-CIN2-PDL-1 Axis
This medical thesis investigates the pivotal role of Programmed Death-Ligand 1 (PDL-1) in the progression and recurrence of high-grade cervical intraepithelial neoplasia (CIN). Focusing on the intricate interplay between human papillomavirus (HPV) and its manifestation as CIN, the study delves into the molecular mechanisms underlying the correlation between the HPV-induced CIN and PDL-1, a key player in the programmed death pathway. The thesis synthesizes current knowledge, offering a comprehensive review to enhance our understanding of the complex interactions driving the development and persistence of high-grade CIN, with implications for potential therapeutic interventions and targeted approaches in cervical cancer management
DOMINONI, MATTIA
Lauree a ciclo unico
File in questo prodotto:
Non ci sono file associati a questo prodotto.

È consentito all'utente scaricare e condividere i documenti disponibili a testo pieno in UNITESI UNIPV nel rispetto della licenza Creative Commons del tipo CC BY NC ND.
Per maggiori informazioni e per verifiche sull'eventuale disponibilità del file scrivere a: unitesi@unipv.it.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14239/16945