An increasing number of bacterial isolates resistant to many, if not all, available antibiotics has lately focused attention of the WHO1 and even of the White House, hosting a Forum on the issue in 2015. Antibiotic resistance is due to antibiotic misuse as well as antibiotic use in different settings such as agriculture and farming. Main culprit organisms are MRSA, VRE, ESBL+ or carbapenemase+ Enterobacteriaceae and Pseudomonadaceae. These latter represent a major problem in Italy. The immediate consequence of bacterial rising multidrug resistance is an impact on the antibiotic stewardship, that is the ever-improving strategy of antimicrobial drug use. Multiple are the issues the antibiotic stewardship has to take into account. One important issue is the appropriateness of either empiric or targeted antibiotic therapy and its continuous objective evaluation.
An increasing number of bacterial isolates resistant to many, if not all, available antibiotics has lately focused attention of the WHO1 and even of the White House, hosting a Forum on the issue in 2015. Antibiotic resistance is due to antibiotic misuse as well as antibiotic use in different settings such as agriculture and farming. Main culprit organisms are MRSA, VRE, ESBL+ or carbapenemase+ Enterobacteriaceae and Pseudomonadaceae. These latter represent a major problem in Italy. The immediate consequence of bacterial rising multidrug resistance is an impact on the antibiotic stewardship, that is the ever-improving strategy of antimicrobial drug use. Multiple are the issues the antibiotic stewardship has to take into account. One important issue is the appropriateness of either empiric or targeted antibiotic therapy and its continuous objective evaluation.
DISCUSSING THE APPROPRIATENESS OF ANTIMICROBIAL TREATMENT AND MULTIDRUG-RESISTANT ORGANISMS: A SIX-MONTH FLASH INSIGHT ON INFECTIONS OCCURRING IN AN INTERNAL MEDICINE DEPARTMENT
BERTUCCIO, FRANCESCO ROCCO
2016/2017
Abstract
An increasing number of bacterial isolates resistant to many, if not all, available antibiotics has lately focused attention of the WHO1 and even of the White House, hosting a Forum on the issue in 2015. Antibiotic resistance is due to antibiotic misuse as well as antibiotic use in different settings such as agriculture and farming. Main culprit organisms are MRSA, VRE, ESBL+ or carbapenemase+ Enterobacteriaceae and Pseudomonadaceae. These latter represent a major problem in Italy. The immediate consequence of bacterial rising multidrug resistance is an impact on the antibiotic stewardship, that is the ever-improving strategy of antimicrobial drug use. Multiple are the issues the antibiotic stewardship has to take into account. One important issue is the appropriateness of either empiric or targeted antibiotic therapy and its continuous objective evaluation.È consentito all'utente scaricare e condividere i documenti disponibili a testo pieno in UNITESI UNIPV nel rispetto della licenza Creative Commons del tipo CC BY NC ND.
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https://hdl.handle.net/20.500.14239/18927