The project of my thesis has the purpose to investigate why some antibodies are more easily produced than others,starting from previous data from our laboratory,suggesting that the factors contribuiting to antibody overproduction may reside at the level of the VH and/or VL structure.Two scFvs derived from anti-phenyloxazolone antibodies were taken into consideration in this thesis: a high-producing one(NQ19/22.21) and a low-producing one(NQ10/2.2.5).
The project of my thesis has the purpose to investigate why some antibodies are more easily produced than others,starting from previous data from our laboratory,suggesting that the factors contribuiting to antibody overproduction may reside at the level of the VH and/or VL structure.Two scFvs derived from anti-phenyloxazolone antibodies were taken into consideration in this thesis: a high-producing one(NQ19/22.21) and a low-producing one(NQ10/2.2.5).
The VH domain amino acid sequence conditions expression levels of two anti-phenyloxazolone scFvs.
RRAPAJ, ENIADA
2017/2018
Abstract
The project of my thesis has the purpose to investigate why some antibodies are more easily produced than others,starting from previous data from our laboratory,suggesting that the factors contribuiting to antibody overproduction may reside at the level of the VH and/or VL structure.Two scFvs derived from anti-phenyloxazolone antibodies were taken into consideration in this thesis: a high-producing one(NQ19/22.21) and a low-producing one(NQ10/2.2.5).È consentito all'utente scaricare e condividere i documenti disponibili a testo pieno in UNITESI UNIPV nel rispetto della licenza Creative Commons del tipo CC BY NC ND.
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https://hdl.handle.net/20.500.14239/21020