The role of the cerebellum has been long neglected in the research and clinical practice in the field of neuropsychological, in particular, in relation to its involvement in in non-motor functions, including, cognition, social cognition and emotion. Specifically, the present thesis focuses on the development of the Cerebellar Cognitive Affective Scale (CCAS-scale), the first available and validated neuropsychological tool for the screening of the Cerebellar Cognitive Affective Syndrome (CCAS), a disorder that affects patients with cerebellar diseases or injury and is characterized by deficits in executive functioning, spatial cognition, language, and affect/emotion regulation. Furthermore, the present thesis presents a study on the standardization of the Italian version of the Cerebellar Cognitive Affective Scale, also including an exploration of the association of the performances in CCAS - scale with demographic and cultural factors and performances in other neuropsychological tests commonly used in the clinical practice. The study included, 103 healthy Italian native speakers, aged between 19 and 95 years (mean age 35.7 ± 17.3; mean education 17.6 ± 4.10; 62% females). Each participant was administered with the Italian version of the CCAS-scale, the Cognitive Reserve Index 4-Questionnaire, and the Coloured Progressive Raven Matrix 5, in a randomized order. Our preliminary results show a positive correlation between performances in the Italian version of the CCAS-scale and those in the Coloured Progressive Raven Matrix. In turn, no significant correlation has been observed between the scorings in the CCAS-Sale and in the Cognitive Reserve Index. The present thesis insights on the importance of development and standardization of the Italian CCAS-scale for the evaluation of the presence of cognitive impairments in patients suffering from cerebellar damages and ultimately highlights the role of cerebellar function in mediated cognitive processes.
Cerebellar Cognitive and Affetcive Syndrom Scale: taratura della versione italiana
PINTO, SIMONA
2022/2023
Abstract
The role of the cerebellum has been long neglected in the research and clinical practice in the field of neuropsychological, in particular, in relation to its involvement in in non-motor functions, including, cognition, social cognition and emotion. Specifically, the present thesis focuses on the development of the Cerebellar Cognitive Affective Scale (CCAS-scale), the first available and validated neuropsychological tool for the screening of the Cerebellar Cognitive Affective Syndrome (CCAS), a disorder that affects patients with cerebellar diseases or injury and is characterized by deficits in executive functioning, spatial cognition, language, and affect/emotion regulation. Furthermore, the present thesis presents a study on the standardization of the Italian version of the Cerebellar Cognitive Affective Scale, also including an exploration of the association of the performances in CCAS - scale with demographic and cultural factors and performances in other neuropsychological tests commonly used in the clinical practice. The study included, 103 healthy Italian native speakers, aged between 19 and 95 years (mean age 35.7 ± 17.3; mean education 17.6 ± 4.10; 62% females). Each participant was administered with the Italian version of the CCAS-scale, the Cognitive Reserve Index 4-Questionnaire, and the Coloured Progressive Raven Matrix 5, in a randomized order. Our preliminary results show a positive correlation between performances in the Italian version of the CCAS-scale and those in the Coloured Progressive Raven Matrix. In turn, no significant correlation has been observed between the scorings in the CCAS-Sale and in the Cognitive Reserve Index. The present thesis insights on the importance of development and standardization of the Italian CCAS-scale for the evaluation of the presence of cognitive impairments in patients suffering from cerebellar damages and ultimately highlights the role of cerebellar function in mediated cognitive processes.È consentito all'utente scaricare e condividere i documenti disponibili a testo pieno in UNITESI UNIPV nel rispetto della licenza Creative Commons del tipo CC BY NC ND.
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https://hdl.handle.net/20.500.14239/3069